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doi: 10.1038/s41586-019-1426-6 22 BeattyASinghTTyurinaYYTyurinVASamovichSNicolasEet al

Topical GHK-Cu can cause local irritation in sensitive patients

In a CLP-induced mouse model of AKI, the E3 ligase MDM2 increased the expression of LMNB1 by promoting the ubiquitinated degradation of p53.LMNB1 may promote mitochondrial damage and ferroptosis in renal tubular epithelial cells and be involved in the development of AKI[22]