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The average quantitation cycle (Cq) value was calculated and the mean Cq value for the housekeeping gene subtracted to determine Cq

Molecular mechanism of HCN action The best known, and described mechanism of HCN toxicity refers to its inhibitory effect on the mitochondrial respiration chain via binding of CN to the ferric heme a 3 of cytochrome c oxidase (COX), the terminal enzyme in Complex IV (Lawson-Smith et al

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6 Thymus Changes in the immune system activity are necessary in the course of a healthy pregnancy as they help to avoid an immune response against an allogeneic fetus (145) ( Table 4 )