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doi: 10.1016/j.phrs.2017.09.010 227 DehzadMJGhalandariHNouriMAskarpourM

Oxeiptosis(oxygen-induced cell death) is a reactive oxygen species (ROS)-sensitive, caspase-independent, non-inflammatory cell death

This finding has led to better understanding of the regulatory mechanism for ROS signals and speculation that DM, DR and retinal cell degeneration are closely associated with ROS-induced hyperglycemia and oxidative stress 8,12,13,14