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The treatment group of 116 patients received a synergistic daily combination of Alpha Lipoic Acid (200 mg) and Coenzyme Q10 (200 mg) for two months, while the remaining 58 patients acted as an untreated control group

Int J Radiat Oncol Biol Phys 10(10):1975-85, 1984

This Notch intracellular domain then translocates to the nucleus, where it forms a complex with CSL and Mastermind-like, regulating target gene expression and influencing critical cellular processes such as inflammation, apoptosis, and proliferation, which are crucial to the pathogenesis of PH as demonstrated by several clinical and preclinical studies (Fig

Interestingly, the PUFA content was downregulated in DLBCL cells (Fig