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doi: 10.1016/j.tips.2020.09.001 207 YinYChoiSCXuZPerryDJSeayHCrokerBPet al

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However, the real effects of L-carnitine supplementation, taking into account its above-mentioned positive and possibly negative properties ( via TMAO), on the process of atherosclerosis and atheroma plaque merit further investigations

Moreover, how oxidative stress and ERS jointly influence specific signaling pathways, such as NF-B, MAPK, SIRT1, and how they affect the balance between autophagy and apoptosis, remains an important question to address