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Scope Adults presenting to the ED with migraine (any ICHD version) Parenteral therapies only (injectable medications and nerve blocks) Randomized controlled trials reporting outcomes within 6 hours Comparators: placebo, sham, or another parenteral therapy Studies included in the 2016 AHS guideline were excluded Evidence Review A systematic review was registered with PROSPERO, approved by the AHS Guideline Committee, and PRISMA guidelines were followed

These findings collectively hint that melatonin may alleviate clinical manifestations of PCOS through its anti-inflammatory and antioxidant pharmacological activities

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Such research is essential for enhancing broodstock quality and facilitating monosex culture strategies