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copper, both contribute to antioxidant defensecopper as an essential mineral enabling enzymatic antioxidant systems, while hydrogen water provides molecular hydrogen that can directly neutralize certain free radicals without copper's potential for pro-oxidant activity at higher concentrations

This work opened the possibility that, in some physiological scenarios, NR could have a unique function

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Frequency of Metformin-Associated B12 Deficiency An association between metformin therapy and B12 deficiency was first reported in 1969