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Studies in IBD patients indicate that TNF levels are increased in the serum, stool, and intestinal mucosa [20] and, correspondingly, patients display increased intestinal paracellular permeability that is characterized by suppression and re-distribution of occludins, and claudins 5,8, whereas claudin-2 expression was upregulated [21]

DSIP stands for Delta Sleep-Inducing Peptide a reference to its proposed role in promoting delta wave sleep, the deepest and most physically restorative stage of the sleep cycle

Tripeptide in human plasma that prolongs survival of normal liver cells and stimulates growth in neoplastic liver. Nature New Biology , 243(124), 8587