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LNPCs were resuspended at a density of 13 10 cells/mL, and 1 10 cells were plated per well in 6-well plates

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Third, by incorporating biomimetic coatings (such as cell membrane camouflage), targeting ligands (e.g., folic acid), and stimuli-responsive shells (like GSH- or H 2 O 2 -sensitive MnO 2 layers), COF nanoparticles gain exceptional control over their biological fate ( Figure 3 )

Next, we extended the isotopologue similarity calculation to all 13 C-labeled metabolites in RPs and non-RPs (see Isotopologue similarity between reaction-paired and non-reaction paired metabolites section in Methods )