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Summaries of various treatment options are provided in Table 10

GA treatment resulted in increased phosphorylation of eNOS and Akt, which subsequently induced NO production and inhibited angiotensin I converting enzyme (Kang et al., 2015)

Research Results Clinically tested for skin irritation on sensitive Skin Clinically tested for non-comedogenic After 1 week : 14.4% improvement in tone evenness* 20.38% improvement in dark spots* 12.89% improvement in dark under-eye circles* 27.04% improvement in redness* 8.72% improvement in eye puffiness* Clinical testing in 20 people

Thus, we propose that GYY4137 represents a promising novel therapeutic strategy for the treatment of OA