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Role of Western diet in inflammatory autoimmune diseases

Mechanistically, the knockdown of miR-32-5p enhanced the radiosensitization and suppressed metastasis of colorectal cancer through directly binding to the 3-UTR of TOB1 mRNA Taken together, miR-32-5p acts as an oncogenic factor in the development of colorectal cancer, which may offer a novel as well as a useful biomarker for the detection of colorectal cancer for diagnosis and prognosis and a potentially successful target for treatment

Unlike the oxidized forms of many other primary and secondary metabolites that can also react with ROS, GSSG is rapidly recycled by the GRs in key organelles and the cytosol (Halliwell & Foyer 1978