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Moreover, psoriasis patients suffer from impaired quality of life with emotional distress and the burden of comorbidities such as hypertension [7], diabetes mellitus [8] and obesity [9] with the increase in the psoriasis severity

6a), apoptotic cell death, or the cleavage of caspase-3, 8, or 9 when combined with TRAIL treatment (Supplementary Fig

Lactylation The aberrant accumulation of lactate in tumors is actively driven by oncogenic events, such as Aurora-A-mediated phosphorylation of LDHB [66]

Furthermore, adding 2 g L 1 of -ketoglutarate (-KG) improved the titer to 1.90 0.06 g L 1 , suggesting that -KG supplement is beneficial to the transamination reactions (Fig