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doi: 10.1126/scitranslmed.3003799 136 ZhouYLiLMaoCZhouD

Mesangial cells in the glomerulus are a special type of smooth muscle cell located between the capillary loops of the glomerular capillaries

Typically, the antigen combining region (or variable region) of a chimeric antibody is derived from a one species source and the constant region of the chimeric antibody (which confers biological effector function to the immunoglobulin) is derived from another source