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It has been described that nutritional interventions with vitamin E and other antioxidants such as vitamin C or melatonin decrease the urinary levels of porphyrins or their precursors in patients affected by different types of porphyria ( Reference Kirshenbaum and Singal 15 Reference Qi, Reiter and Tan 19 )

beta-Hydroxybutyrate activates the NF-kappaB signaling pathway to promote the expression of pro-inflammatory factors in calf hepatocytes

Elsevier, pp

Additionally, granulosa cells in women with endometriosis exhibit apoptosis, mitochondrial dysfunction, disrupted steroid hormone production, and increased inflammatory markers, further compromising follicle health ( These changes contribute to significant oocyte quality defects