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Description

J Emerg Med 2012

The oxygen gradient in the intestinal mucosa is crucial for maintaining intestinal homeostasis, while IBD patients often exhibit significant mucosal hypoxia

Recent animal research suggests this drug inhibits ATP citrate lyase (ACL), an enzyme involved in cholesterol and fatty acid synthesis

It is considered the master regulator of inflammation, controlling the expression of hundreds of genes involved in immune activation, cytokine production, and cell survival