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Population pharmacokinetics of dexmedetomidine during long term sedation in intensive care patients British Journal of Anaesthesia Drug Half life Explained: Calculator, Variables & Examples Pharmacokinetics and Pharmacodynamics: Rational Dosing and the Time Course of Drug Action Basic and Clinical Pharmacology, 13th Ed. Rishi In any basic pharmacology course, we're taught the concept of an "elimination half life," or the time it takes to reach 50% of a drug's initial concentration. However, with more advanced
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