foxo4-dri senolytic 2023 2024 study induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation Senolytics: from pharmacological inhibitors to
Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment npj Aging ES2 rapidly destroys TP53 FOXO4 foci leading to TP53 mediated Download Scientific Diagram The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect
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