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However, at a pH below 6, secondary nucleation is favoured than fibril growth thus shifting the kinetics of fibrillation towards formation of toxic protofibrils (Frey et al., 2024)

Arterial occlusion often originates from thromboembolism, where blood clots originating elsewhere in the body lodge within the mesenteric arteries, blocking blood flow (Yu and Kirkpatrick, 2023)