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In a way, theyre kind of like text messages between cells, helping coordinate recovery, growth, and repair

Phosphorylation of IRF3 by TBK1 dimerizes and translocates IRF3 to the nucleus, inducing the expression of the type I interferon (IFN) gene, interferon-stimulated genes (ISGs), and several other inflammatory mediators, pro-apoptotic genes, and chemokines, which in turn are involved in various pathophysiological processes (141, 145, 146) ( Figure 2 )

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