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By replacing and mimicking thymosin Beta-4 peptide, the TB-500 nasal spray may influence similar pathways in subjects in the investigational trials

The pan-caspase inhibitor zVADfmk, partially blocked the induction of apoptosis at 48 h, and was ineffective after 72 h

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All results from the literature refer to cytotoxic activities in different tumor cell lines (A549, MCF-7, SKOV3, PC-3, HepG2, U937) but not to animal experiments or human studies (Chang et al., 2015)