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Recent advances in single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, spatial proteomics, and patient-derived models have begun to reshape our understanding of chemoresistancenot as a static trait, but as a dynamic and heterogeneous process shaped by both tumor cell plasticity and microenvironmental cues

In this study, we discovered for the first time that fresh 316ss possessed an intrinsic peroxidase (POD) catalytic activity, which can catalyze the substrate of POD-like reaction 3,3,5,5-tetramethylbenzidine (TMB) changing to a blue-colored product, oxidation of TMB, in the presence of hydrogen peroxide (H 2 O 2 )

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doi:10.1128/msystems.00001-18 88