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Since fat burning is the main source of muscle energy, l-carnitine deficiencies translate into low energy levels and muscle weakness

Acetyl L-Carnitine is produced within the kidneys and liver and is transported and used by other tissues of the body

The partial rescue of the above-described symptomatology can be ascribed to the activity of other transporters such as ATB 0,+ (SLC6A14), MCT9, and probably, OCTN1 (SLC22A4) that accept carnitine with a much lower affinity if compared to OCTN2

Abstract The androgen receptor (AR) is a ligand-activated transcription factor that is a major driver of lethal prostate cancer (CaP) progression