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1018 These findings position ND-646 as a promising candidate for cancer therapy, emphasizing its potential utility in oncology

Bajaj JS, Fagan A, Gavis EA, Kassam Z, Sikaroodi M, Gillevet PM

2299-C DISSECTING THE ROLES OF THE TWO HOMOLOGOUS PHOSPHOLIPID SCRAMBLASES: TMEM41B AND VMP1, IN NAFLD/NASH Allen Chen, Wen-Xing Ding and Hong-Min Ni, University of Kansas Medical Center, Kansas City, KS Background: Transmembrane Protein 41B (TMEM41B) and Vacuolar Membrane Protein 1 (VMP1) are homologous endoplasmic reticulum (ER)-resident scramblases with important roles in autophagy and VLDL secretion