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The symptoms of insulinoma occur as a result of elevated insulin levels in the blood, usually manifesting as neuroglycopenic and autonomic symptoms [66, 67]

Firstly, although many drugs show promising results in animal models, there is a lack of sufficient large-scale clinical trial data to support their efficacy and safety across diverse patient populations (206)

have discovered that berberine improves cardioprotection by upregulating miR-340-5p and inhibiting high mobility group box 1 (HMGB1)-mediated inflammatory response (Long et al., 2023)

47 Chalcones (1,2-diphenyl-2-propen-1-one) belonging to the flavonoid family, such as isoliquiritigenin (licorice roots) and xanthohumol (hops), have been shown to decrease pulmonary inflammation caused by lipopolysaccharide (LPS)