foxo4-dri senolytic peptide mechanism

foxo4-dri senolytic peptide mechanism Class II senolytics inhibit survival pathways elicited by senescent FOXO4-DRI For Sale (10mg) -

Name: foxo4-dri senolytic peptide mechanism Class II senolytics inhibit survival pathways elicited by senescent FOXO4-DRI For Sale (10mg) -
Brand: trustt.digital
SKU: 4382325340
Price: 24.21 USD
Availability: InStock
Rating: 4.0837 (12 reviews)

FOXO4 DRI For Sale (10mg) Core Peptides Peptide Inhibitors Targeting FOXO4 p53 Interactions and Inducing Senescent Cancer Cell specific Apoptosis Journal of Medicinal Chemistry Development of a novel senolytic by precise disruption of FOXO4 p53 complex eBioMedicine The FOXO4 peptide in a DRI conformation (D amino acids in a retro reversed sequence), henceforth named FOXO4 DRI, competes with FOXO4 for p53 binding in a dose dependent manner and doing so with higher affinity.

SKU: 4382325340 · From trustt.digital

4.1

USD24.21 USD57.21

Pay in 4 interest-free payments of $6.05 Learn more

Shipping Estimate
USA

USA

CAN

Ships within 48 hours · Estimated delivery Aug 1 - Aug 6

Description

Efforts to optimize its hydrophobic nature have enhanced brain bioavailability, as evidenced by preclinical studies on ddY and 5FAD mouse models (Tohda et al., 2017)