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The Classical (1990) definition uses the following criteria: 1) 100 or more melanocytic nevi, 2) one or more melanocytic nevi greater than or equal to 8mm in its largest diameter, and 3) one or more clinically atypical melanocytic nevi

The brown and black colors usually arise as a result of melanin pigmentation

A: Researchers commonly compare MT1 and MT2 because they are associated with different melanocortin and pigmentation pathway characteristics

Evidence from randomized controlled clinical trials that included patients with melanomas of this size suggests that they may be adequately treated with radial excision margins of 1 cm