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Such studies remind us that negative or nuanced outcomes are often the most enlightening, pushing the field forward and helping refine both scientific questions and clinical practice

However, ignoring a sprained finger with the hope that it will heal on its own may lead to long-term problems, including chronic instability, weakness, stiffness, and arthritis

Enhanced oxidative capacity may involve increased mitochondrial fatty acid uptake via carnitine palmitoyltransferase-1 (CPT-1), enhanced beta-oxidation enzyme expression, and modulation of uncoupling protein expression

Two groups were matched for age, gender, comorbidities, and other soft tissue and inflammatory issues, HbA1c, sleep apne, BMI, opioid use, NSAID use, antidepressants