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Moreover, peripheral inflammation post-COVID may have long-term consequences, such as dementia and neurodegenerative disease, which can be further promoted by an unhealthy diet (Butler and Barrientos, 2020)

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TB-500 (a synthetic peptide fragment of thymosin beta-4) enhances cellular migration and blood vessel formation primarily through actin regulation and upregulation of angiogenic factors

Although direct data are not available linking disturbances in these limbic/paralimbic areas to inflammation in bipolar disorder, it tempting to speculate that their aberrant activity may have a causal role in the ensuing immune dysregulation that has been repeatedly observed in patients with bipolar illness