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[26] On the other hand, presence of ALDH2*2 in East Asians (a variant of the ALDH gene), can cause blood acetaldehyde levels of 30 to 75 M or higher, which is more than 10 times the normal level

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Because the 0.9% benzyl alcohol preservative allows repeated withdrawals without re-sterilising the vial, a single 10ml supply can support multiple reconstitution events across a single research project, reducing both cost and vial waste compared to single-use sterile water for injection.

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AstraZenecas esomeprazole (Nexium) lifecycle illustrates this: after omeprazole generics flooded the market, AstraZeneca launched the S-enantiomer with new method-of-use patents covering specific GERD indications, buying several additional years of premium pricing

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