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We performed xCELLigence proliferation analysis to evaluate the impact of NAC on the proliferative capacity of endometriotic cells in response to inflammatory cytokines in a time- and dose-dependent manner

Chronic high glucose (25 mM) induces endoplasmic reticulum (ER) stress characterized by activation of the PKR-like endoplasmic reticulum kinase (PERK)/eukaryotic translation initiation factor 2 (eIF2)/C/EBP homologous protein (CHOP) axis, increased ROS accumulation, upregulation of pro-apoptotic BCL2 associated X apoptosis regulator (Bax) and Bcl-2-associated death promoter (Bad), caspase-3 cleavage, and enhanced apoptosis

101 Despite progress, clinical translation of nanozyme-based AP therapy is hindered by limited preclinical models and passive delivery, long-term biosafety concerns (metal ion leaching), and challenges in scalable manufacturing

Volume is typically 0.05 mL per injection, with morning injections most commonly reported