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[Google Scholar] Capo-chichi LJ, Eilitta M, Carsky RJ, Gilbert RA, Maasdorp B

CYP2E1 is a well-known leaky enzyme (due to the constitutive high spin form of this enzyme) with a unique ability to produce ROS and other radical intermediates during the catalytic cycle (Harjumaki et al

However, our data suggest that following GSH depletion, NRF2 is stabilized, and this stabilization is associated with decreased expression of lipogenic enzymes and lower serum triglyceride levels