parkinson glutathione oxidative ipsc crispr stress monitoring in iPSC-derived motor neurons using genetically encoded biosensors of H2O2 CRISPR/Cas9 assisted stem cell therapy
CRISPR Cas9 assisted stem cell therapy in Parkinson's disease Biomaterials Research Springer Nature Link Ferroptosis is a type of cell death driven by uncontrolled peroxidation of membrane phospholipids. Glutathione peroxidase 4 (GPX4) is the main regulator of ferroptosis, but how it protects membranes is not well Frontiers Mitochondrial Dysfunction in Parkinson's Disease: From Mechanistic Insights to Therapy Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether phospholipid membrane composition: Cell Reports
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