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Besides, a variety of SIRT1 activators have been used to prevent and treat senesence-related renal deficiency (Zhao and Yu., 2021), SRT 1720 (Ren et al., 2017), SRT2183 (Koh et al., 2018), Isoliquiritigenin (Zou et al., 2018)

[11] In summary, while alpha-lipoic acid is generally compatible with many medications, it can amplify blood sugar-lowering drugs and alter thyroid hormone activity, among other interactions, so proactive monitoring and consultation with healthcare professionals are essential