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Description

This study aimed to evaluate the toxic effect of the simultaneous exposure of the undifferentiated human SH-SY5Y neuroblastoma cell line to MDMA and tramadol or MDMA and tapentadol, focusing on serotonin toxicity

Ghrelin receptor / GHSR signalling studies

Most notably, ALA upregulates gamma-glutamylcysteine ligase (-GCL), the rate-limiting enzyme required for the synthesis of glutathionethe body's master intracellular antioxidant

Cellular deconvolution of bulk transcriptomic data from the peri-infarct cortex showed that cells with molecular signature similar to the so-called disease-associated astrocytes, originally described in the vicinity of -amyloid plaques in a mouse model of AD and in the aged brain 464 , are present also in post-stroke tissue 383