number: P10144) medium and stored at -20 C until digitalization
Weeks 9 through 12: GHK-Cu 2mg subcutaneous injection every other day
Associated clinical sites Willemsen R (Barts Health NHS Trust, UK), Smith A (Northampton General Hospital NHS Trust, UK), Anand B (West Suffolk NHS FT, UK), Puthi V (North West Anglia NHS FT, UK), Zac-Varghese S (East & North Hertfordshire NHS Trust, UK), Datta V (Norfolk & Norwich University NHS FT, UK), Dias R (Birmingham Womens and Childrens NHS FT, UK), Sundaram P (University Hospitals of Leicester NHS Trust, UK), Vaidya B (Royal Devon & Exeter NHS FT, UK), Patterson C (NHS Fife, UK), Owen K (Oxford University Hospitals NHS FT, UK), Dayan C (Cardiff & Vale University Health Board, UK), Piel B (Queen Elizabeth Hospital, Kings Lynn FT, UK), Heller S (Sheffield Teaching Hospitals NHS FT, UK), Randell T, Gazis T (Nottingham University Hospitals NHS Trust, UK), Bismuth Reismen E, Carel J-C (Hospital Robert Debre, France), Riveline J-P, Gautier J-F (Hospital Lariboisiere, France), Andreelli F (Hospital Lapitie-Salpetriere, France), Travert F (Hospital Bichat Claude Bernard, France), Cosson E (Hospital Jean-Verdier, France), Penfornis A, Petit C (Centre Hospitalier Sud-Francilien, France), Feve B (Hospital St Antoine, France), Lucidarme N (Hospital Jean-Verdier Pediatrie, France), Cosson E (Hospital Avicenne, France), Beressi J-P (Hospital Andre Mignot, France), Ajzenman C (Hospital Andre Mignot Pediatrie, France), Radu A (Hospital Europeen Georges-Pompidou, France), Greteau-Hamoumou S (Hospital Louis Mourier, France), Bibal C (Hospital Kremlin Bicetre, France), Meissner T (Universitatsklinikum der Heinrich-Heine-Univeritat Dusseldorf, Germany), Heidtmann B (Katholisches Kinderkrankenhaus Wilhelmstift, Germany), Toni S (AOU Meyer, Italy), Rami-Merhar B (Medical University of Vienna, Austria), Eeckhout B, Peene B, Vantongerloo N (Algemeen Ziekenhuis Geel Sint-Dimpna Geel, Belgium), Maes T, Gommers L (Imeldziekenhuis Bonheiden, Belgium)
While animal studies consistently demonstrate beneficial effects across diverse injury models and tissue types, the absence of adequately powered, controlled human clinical trials prevents definitive conclusions about efficacy in human disease
