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Similar data were reported by Bot et al

The formation and progression of cysts in ADPKD are also associated with oxidative stress, inflammation, and cell death (268, 269)

Russ Chem Bull

Nicotinamide N-methyltransferase (NNMT) is a cytoplasmic enzyme that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM, the universal methyl donor) to nicotinamide (the NAD + salvage precursor), producing 1-methylnicotinamide and S-adenosyl-L-homocysteine