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Koeth et al., 2013)

Vedam SS, Kini VR, Keall PJ, Ramakrishnan V, Mostafavi H, Mohan R

Additionally, apremilasts efficacy extends beyond plaque psoriasis to difficult-to-treat cases such as palmoplantar and scalp psoriasis, where significant symptom improvement has been documented (Rich et al

ATZ was observed to downregulate key steroidogenic enzymes, including 3-HSD and Cyp17a1 , and disrupt the expression of genes critical for testosterone production, such as StAR 8,9,10