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Glutamine-derived -ketoglutarate is oxidized into oxaloacetate to maintain the production of citrate

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Finally, this pathway also modulates the tumor immune microenvironment through metabolic reprogramming, as illustrated in Figure 1

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After complete extraction, the solvent was removed by rotary evaporation

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Other proteins induced by NRF2 synthesize quinones and peroxiredoxins, potent protective agents

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