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Finally, iron overload, in combination with decreased IRP1 content, was noticed [33]

Primary and secondary results of LUMINESCE, a Phase 3 study of interleukin-6 signaling inhibition by satralizumab in generalized myasthenia gravis

however, the positive or negative effect of NOs role in enhancing the production of reactive oxygen species ultimately depends on the balance between reactive oxygen species and antioxidant production (Pappas et al., 2023)