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This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 52 print issues and online access 199,00 per year only 3,83 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

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DOI: 10.1016/j.schres.2012.12.019 53

However, the preponderance of extant evidence derives from animal models and preclinical studies, which may not fully capture the complexity of human disease