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References NIH Office of Dietary Supplements: Vitamin B12 Fact Sheet for Health Professionals National Heart, Lung, and Blood Institute: Vitamin B12-Deficiency Anemia FDA: Advises Consumers Not to Inhale Nitrous Oxide Products, March 2025 Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study, Journal of Clinical Endocrinology and Metabolism UCSF: B12 Levels Within the Normal Range Linked to Cognitive Decline, Annals of Neurology Excess Folic Acid and Vitamin B12 Deficiency: Clinical Implications

Several studies have also reported that KD activates the antioxidant pathways, including Nrf2 signaling, supporting its role in modulating mitochondrial dysfunction and oxidative stress that contribute to dopaminergic neurodegeneration in PD models [69]

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84 It thus may be speculated that the formation of presumably senescent foam cells 85 in atherosclerotic plaques gets prevented by intensive statin therapy