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While human clinical trials provide valuable insights, complementary studies using animal models are essential to elucidate these mechanisms

Preparation, optimization and biological evaluation of gymnemic acid loaded niosomes against streptozotocin-nicotinamide induced diabetic-nephropathy in Wistar rats

[195] prepared electrospun nanofibers serving as carriers for ZnO 2 NPs, Fe 3 O 4 NPs, and polyacrylic acid (PPF/PZ nanofibers), in which polyacrylic acid can provide H + to promote the production of H 2 O 2 , provide an acidic environment and sufficient substrate for the nanozymes to exert POD-like activity, and increase the production of OH to kill bacteria