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Notably, we demonstrate that S -glutathionylation of C23 or C204 of OTUB1 promotes binding of the E2-conjugating enzyme UBCH5A, leading to stabilization of SCL7A11 and augmentation of GSH in a GLRX-reversible manner

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ALX148 Is a High Affinity Sirp Fusion Protein That Blocks CD47, Enhances the Activity of Anti-Cancer Antibodies and Checkpoint Inhibitors, and Has a Favorable Safety Profile in Preclinical Models

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