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doi: 10.3233/JAD-2012-120013 312 ChandKRajeshwariCandeiasECardosoSMChavesSSantosMA

Among them one by GSH, an abundant tripeptidyl molecule, contributes to the body and lung health status ( Resistance to viral diseases positively correlates with the extent of GSH stores ( Interestingly, preventive supplementation of NAC significantly reduced the incidence of clinically apparent influenza, especially in higher risk elderly population ( The deficiency of GSH in the alveolar fluid in ARDS patients was found to correlate with the increased ROS-mediated lung cell injury and inflammation (Soltan-Sharifi et al., 2007): Soltan-Sharifi also reported that supplemental NAC resulted in the prevention of this aggravating condition (Soltan-Sharifi et al., 2007)

These alterations impair nutrient absorption, reduce the bioavailability of amino acids including leucine, and contribute to chronic low-grade inflammation that exacerbates anabolic resistance and endothelial dysfunction