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doi: 10.1006/mgme.2000.3093

EZH2 represses IGFBP1 (a decidualization marker) by increasing H3K27Me3 at the IGFBP1 promoter, impairing decidualization, while EZH2 knockdown or conditional deletion in mouse ESCs rescues decidualization defects and improves fertility ( Chromatin remodeling factors also play a pivotal role

In adults, however, apoptosis also contributes to the development of the neurodegenerative diseases through axonal degeneration and neuronal cell death (Pemberton et al., 2021)

Overexpression of CXCR4 in acute myeloid leukemia predicts adverse overall and progression-free survival independently of FLT3 gene mutation