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N Engl J Med 323 : 16 Taaffe DR et al

Iron Utilization Erythropoiesis and the Role of Bone Marrow Bone marrow cells capture the complex of ferric iron ions and transferrin through transferrin receptors (transferrin receptor protein 1, TfR1), whose synthesis increases during periods of heightened demand for red blood cells (erythrocytes), such as during regular high-intensity endurance training