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A randomized trial in Stress and Health found that stressed adults with low magnesium who received magnesium plus vitamin B6 showed greater daily activity and reduced stress within eight weeks

Other types, like hydroxocobalamin, might be used for different reasons

The most useful investigation is an MRI scan of the brain with and without contrast, which is used to rule out other potential causes of pain if the diagnosis is not clear cut or if red flags are present

Current evidence suggests that simple fatty liver does not directly cause B12 deficiency, but the metabolic conditions, medications, and dietary patterns often associated with fatty liver can increase deficiency risk