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doi: 10.3390/toxins11090527 122 Fernndez-MosqueraLDiogoCVYambireKFSantosGLLuna SnchezMBnitPet al

Inflammation can damage lung tissue and induce DNA damage in lung cells, mitochondrial DNA damage leads to the dysregulation of mitochondrial quality control, which lays the foundation for the malignant transformation from stage II (such as pulmonary fibrosis) to stage III (lung cancer), thereby increasing the risk of lung cancer (Taucher et al., 2022)