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Although the water quality guideline for atrazine in aquatic ecosystems is 10 g/L as stipulated by the Department of Water Affairs and Forestry (DWAF 1996), this guideline has not been updated since 1996 and there are also no guidelines for water used for livestock watering or irrigation in the agricultural sector

Furthermore, whereas the biallelic inactivation of NF1 in neoplastic Schwann cells is critical for cNF formation, it is still unclear which additional genetic, transcriptional, epigenetic, microenvironmental or endocrine changes are important

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