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238 This complicates mechanistic interpretation and may lead to false-positive or irreproducible findings in high-throughput screening

Given the complexity of mechanisms involved in drug resistance and survival pathways of tumor cells, combination strategies of GSH-conjugates with conventional chemotherapy or targeted drugs should provide very interesting perspectives for the treatment of drug resistant tumors

doi: 10.3389/fpsyt.2022.813304 Received 12 November 2021 Accepted 24 January 2022 Published 01 March 2022 Volume 13 - 2022 Edited by Ignazio Piras, Translational Genomics Research Institute (TGen), United States Reviewed by Ahmed Nadeem, King Saud University, Saudi Arabia

If irritation persists, reduce usage or discontinue